"The 22-250 Remington is based on the necked down 250-3000 case with the shoulder angle changed to 28 degrees. In 1967, thirty years after the original wildcat versions, Remington began production of this cartridge in their Model 700 Series rifles.
The 22-250 is only slightly less powerful than the 220 Swift and yet is more versatile. It readily handles reduced loads and has been used for a great variety of hunting, from varmints to deer. The 22-250 stands out as a potent cartridge best suited for varminting.
Varget gives excellent accuracy throughout the full range of Hornady Bullets. Shooters using the 45 grain Hornet bullet should note that the maximum velocity listed is 3600 fps. It is designedto expand at 22 Hornet velocities and therefore has too thin a jacket to fe fired at velocities higher than 3600 fps. At velocities exceeding 3400 fps, bullets sometimes come apart before they reach the target. Also, note the thin jacket of SX bullets limits them to velocities of 3400 fps. As in many of the larger 22s, the heavier bullets are normally the best choice for optimum performance. The Hornady line offers an excellent number of choices, including the spectacular 22 V-MAX bullets. The Hornady 40 grain V-MAX loaded with Varget makes a spectacular combination for prairie dogs!
Exercise caution when storing and shooting ammunition loaded with ball powders. Such powders are subject to pressure excursions when left in hot storage locations."